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| Title: | Oxygen Toxicity Risk Assessment. |
| Authors: | Vann, RD |
| Keywords: | Oxygen Toxicity
oxygen
Respiration
RISK
BREATHING APPARATUS
partial pressure
PULMONARY OXYGEN TOXICITY
FREE RADICALS
CYTOLOGY
TISSUES(BIOLOGY) |
| Issue Date: | 1988 |
| Publisher: | DUKE UNIV MEDICAL CENTER DURHAM NC |
| Citation: | ADA299552 |
| Abstract: | Oxygen toxicity is a consequence of breathing oxygen partial pressures greater than in atmospheric air. While oxygen itself is not toxic, the evidence indicates that toxic derivatives of oxygen are a by-product of cellular respiration. The production of toxic oxygen species increases as the tissue oxygen tension rises (Yusa et al. l987), and toxicity probably occurs due to tissue damage or interference with normal function. The toxic oxygen species produced in normoxic conditions are deactivated, but under hyperoxic conditions they accumulate. The balance between production and removal of toxic species is well-suited to mathematical modelling and statistical analysis. |
| Description: | Citation Status: Active; Citation Classification: Unclassified; Title Classification: Unclassified; Report Classification: Unclassified; Identifier Classification: Unclassified; Abstract Classification: Unclassified; Distribution Limitation(s): 01 - APPROVED FOR PUBLIC RELEASE; Information provided by the Department of Defense and the Defense Technical Information Center (http://www.dtic.mil/) is considered public information and may be distributed or copied unless otherwise specified. Use of appropriate byline/photo/image credits is requested. |
| Gov't Doc # : | ADA299552
N00014-87-C-0283 |
| URI: | http://archive.rubicon-foundation.org/4103 |
| Appears in Collections: | Undesignated and Unpublished Reports
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Description |
Size | Format |
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| ADA299552.pdf | | 977Kb | Adobe PDF | View/Open |
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