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| Title: | Acute decompression illness and serum s100beta levels: a prospective observational pilot study. |
| Authors: | Poff, DJ
Wong, R
Bulsara, M |
| Keywords: | DIVERS
decompression sickness
decompression illness
neurological
biochemical marker
serum S100beta
Creatine Kinase
human |
| Issue Date: | 2007 |
| Publisher: | Undersea and Hyperbaric Medical Society |
| Citation: | Undersea Hyperb Med. 2007 Sep-Oct;34(5):359-67. |
| Abstract: | BACKGROUND: S100beta, a calcium binding protein associated with astroglial cells and other tissues has been shown to be raised in the serum of patients with a number of neurological pathologies. As there are no published data on serum S100beta determinations in recreational divers affected by decompression illness (DCI) this pilot study determines whether S100beta is a possible biochemical marker of DCI worthy of further investigation. METHODS: Venous blood samples were drawn from patients diagnosed with, and treated for acute DCI at a hyperbaric facility and analysed for serum S100beta concentration and Creatine Kinase (CK) activity. Samples were taken at initial presentation, and again following final treatment. RESULTS: Twenty one patients were included in the study. Neither S100beta, nor CK levels were significantly raised above population normal limits. CONCLUSION: S100beta is not a clinically useful serum marker of acute DCI. |
| Description: | Undersea & Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc. |
| URI: | http://archive.rubicon-foundation.org/8036 |
| ISBN: | 1066-2936 |
| Appears in Collections: | Undersea and Hyperbaric Medicine Journal
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| 18019087.pdf | | 1618Kb | Adobe PDF | View/Open |
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