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Title: A Statistical Analysis of Recent Naval Experimental Diving Unit (NEDU) Single-Depth Human Exposures to 100% Oxygen at Pressure.
Authors: Harabin, AL
Survanshi, SS
Keywords: Oxygen Toxicity
oxygen
CENTRAL NERVOUS SYSTEM
MATHEMATICAL MODELS
FUNCTIONS
Risk Assessment
RISK
ADHESION
Depth
CASE STUDIES
exercise
EXPOSURE(PHYSIOLOGY)
EXERCISE(PHYSIOLOGY)
INTERVALS
hyperbaric conditions
ACCUMULATION
RESPIRATION
SAFETY
PURGING
SIGNS AND SYMPTOMS
PROBABILITY
PREDICTIONS
human
Issue Date: 1993
Publisher: NAVAL MEDICAL RESEARCH INST BETHESDA MD
Citation: ADA273488
Abstract: Using the data from 688 human single-depth hyperbaric oxygen (02) exposures conducted at the Naval Experimental Diving Unit and reported on from 1979-1986, we developed a mathematical model that can predict the risk of developing symptoms of central nervous system 02 toxicity as a function of time and depth of exposure. Maximum likelihood analysis with models relating depth and time of exposure to risk accumulation was used to estimate probability of symptom development and confidence intervals. U.S. Navy single depth-time 02 diving limits were evaluated for safety as a function of actual P02 achieved in the breathing apparatus. These results suggest that current limits are not of equal risk. Long shallow exposures might present unacceptably high risk if an F102 = 1.0 were achieved in the breathing rig. Adherence to current recommended purging procedures results in acceptably low (< 1%) risk predictions for all depths.
Description: Citation Status: Active; Citation Classification: Unclassified; Title Classification: Unclassified; Report Classification: Unclassified; Identifier Classification: Unclassified; Abstract Classification: Unclassified; Distribution Limitation(s): 01 - APPROVED FOR PUBLIC RELEASE; Information provided by the Department of Defense and the Defense Technical Information Center (http://www.dtic.mil/) is considered public information and may be distributed or copied unless otherwise specified. Use of appropriate byline/photo/image credits is requested.
Gov't Doc # : ADA273488
NMRI-93-59
URI: http://archive.rubicon-foundation.org/5028
Appears in Collections:Naval Medical Research Center (NMRC)

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