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| Title: | 100% OXYGEN MANAGEMENT OF CHRONIC DEGENERATIVE CNS AND NUEROENDOCRINE "AUTOIMMUNE" DISEASE SYNDROMES: (SPECIFICALLY NEUROUROLOGIC SYMPTOMS ASSOCIATED WITH MULTIPLE SCLEROSIS). |
| Authors: | Van Allen, HW |
| Keywords: | Hyperbaric Oxygenation
neurological
Normobaric conditions
auto-immune disease
multiple sclerosis
human
neurourinary
aquatic environment |
| Issue Date: | 1981 |
| Publisher: | Undersea and Hyperbaric Medical Society, Inc. |
| Abstract: | 1. A small (n = 13) prospective pilot study compared intermittent daily hyperbaric chamber versus homecare "normobaric" 100% oxygen therapy in a heterogeneous chronic
(14.1 year duration KDSS = 5.2) multiple sclerosis population. Both protocols provided no significant change in KDSS but did have similar transient significant (p < 0.05) subjective neuro-urinary response. Weekly "booster" sessions were required to maintain this response. 2. Then a single blinded, placebo (compressed air) controlled study was conducted on a heterogeneous MS population (n = 32, mean KDSS = 5.4) to determine the efficacy of weekly 1 ATA to 1.2 ATA 100% 02 therapy. The unknown gas was administered once per week during a disabled "scuba" aquatics program using a demand regulator. Differential (p < 0.10) subjective neurourinary response was demonstrated only at the lATA pp02 concentration. -note: The cool and buoyant aquatic environment itself had a significant (p < 0.10) impact on both objective KDSS and subjective neuro-urinary parameters. 3. Next a comprehensive unblinded longitudinal triple crossover study with ten advanced (11.0 year KDSS = 6.4) chronic progressive/stable patients acting as their own control, examined the therapeutic dose-response to varying protocols using homecare administered 1 ATA 100% oxygen. Once again, significant (p < 0.05) transient differential subjective neurourologic response was demonstrated. |
| Description: | Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 26-30, 1987. The Hyatt Regency Hotel, Baltimore, Maryland (http://www.uhms.org) |
| URI: | http://archive.rubicon-foundation.org/5566 |
| Appears in Collections: | UHMS Meeting Abstracts
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