[abstract] HEALTH RELATED QUALITY OF LIFE (HRQL) FOLLOWING CARBON MONOXIDE POISONING.

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[abstract] HEALTH RELATED QUALITY OF LIFE (HRQL) FOLLOWING CARBON MONOXIDE POISONING.

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Title: [abstract] HEALTH RELATED QUALITY OF LIFE (HRQL) FOLLOWING CARBON MONOXIDE POISONING.
Author: Churchill, S; Hopkins, RO; Weaver, LK; Chan, KJ; Haberstock, D
Abstract: BACKGROUND: Cognitive sequelae occurs following CO poisoning, yet, information is lacking about HRQL outcome in CO-poisoned patients. We will report prospectively-collected HRQL outcome in CO-poisoned patients. MATERIAL AND METHODS: CO-poisoned patients recruited for a clinical trial1 were administered the Medical Outcome Study Short Form (SF-36) at 2-weeks, 6-weeks, 6-months, and 12-months post-CO poisoning. We compared 2-week SF-36 data to normative data and compared time and treatment (HBO2 vs. NBO2)1 for the total, cognitive sequelae and no-sequelae groups (RMANOVA). Also, HRQL data will be compared in those with and without cognitive sequelae RESULTS: The CO-poisoned patients' data differed from normative data on 6 of the health concepts at 2 weeks. Scores improved across time (p less than 0.001 to 0.03), but not for HBO2 or NBO2 treatment, or the time-by-treatment interaction. Health concepts for those with cognitive sequelae vs. no-sequelae were lower in the sequelae group for some domains before 12 months (mean +/- SD (N). (The table reports findings that were significant.). 2-weeks General 6-weeks General Physical Social Health Physical Social Health, Sequelae 75.8+28.2 (46) 64.1+25.6 (46) 64.3+19.4 (46) 80.2+31.1(44) 72.4+25.1 (44) 63.0+22.2 (44), No Sequelae 89.2+19.9 (95) 76.7+24.2 (95) 71.3+21.7 (95) 91.9+15.5 (95) 84.9+23.1 (95) 71.6+21.6 (95), p-value 0.005 0.005 0.069 0.022 0.005 0.030, 6-months General 12-months General, Physical Social Health Physical Social Health, Sequelae 77.7+31.0 (39) 77.9+22.8 (39) 61.5+23.2 (39) 82.9+25.3 (33) 84.5+22.1 (33) 73.6+20.7 (33)No Sequelae 90.9+18.0 (76) 84.9+24.9 (76) 73.4+19.7 (76) 91.2+17.8 (83) 86.6+21.3 (83) 71.8+21.4 (83), p-value 0.017 0.147 0.005 0.091 0.632 0.676. CONCLUSIONS: 1) CO-poisoned patients have decreased HRQL (SF-36), which improved over time. 2) Overall, there were no differences between the sequelae and no-sequelae group for HRQL. 3) CO-poisoned patients with sequelae had decreased HRQL for physical function, social function and general health that were normal by 1-year. 4)The SF-36 may be insensitive to detect post CO-poisoning cognitive sequelae, especially by 1-year. 1. Weaver LK, et al. Undersea Hyper Med 2001;28(supl);15. Supported by the Deseret Foundation, LDS Hospital.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/1132
Date: 2002

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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