Effects of age and magnesium ions on oxygen toxicity in the neonate chicken

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Effects of age and magnesium ions on oxygen toxicity in the neonate chicken

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dc.contributor.author Torley, LW en_US
dc.contributor.author Weiss, HS en_US
dc.date.accessioned 2006-08-24T02:54:36Z
dc.date.available 2006-08-24T02:54:36Z
dc.date.issued 1975 en_US
dc.identifier.other Undersea Biomed Res en_US
dc.identifier.uri PMID: 15622741 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/2432
dc.description Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.description.abstract White Leghorn male chicks, 2-6 days and 4 weeks old, were injected with MgCl2 (2 mM Mg/kg body weight) and exposed to 100% O2 at 75 lb/in2 (approximately 5 atm). Compared to saline-injected controls, average time to onset of convulsions was delayed 37% in the younger group with no significant difference in the protective effect during days 2-6. The delay in onset of convulsions was 66% in the 4-week-old group. The protective action of Mg++ in the chick agrees closely with that reported for the mature rat. Chicks treated with Mg++ did not appear depressed. Susceptibility to hyperbaric O2 convulsions increased uniformly between the 2nd and 6th day, with time to onset of convulsions decreasing by 1.4 min/day from the 19.3 +/- 1.01 (SE) min observed at day 2 for saline controls. Between the 6th and 28th day, susceptibility was relatively stable with time to onset decreasing by about 0.2 min/day in controls. en_US
dc.format.extent 702949 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.source.uri null en_US
dc.subject hyperbaric en_US
dc.subject age en_US
dc.subject magnesium ions en_US
dc.subject oxygen toxicity en_US
dc.subject animal en_US
dc.subject chicken en_US
dc.subject.mesh Animals Animals, Newborn Chickens Hyperbaric Oxygenation/adverse effects* Magnesium/therapeutic use* Magnesium Chloride/therapeutic use Male Oxygen/poisoning* Seizures/etiology Seizures/prevention & control* Sodium Chloride/therapeutic use Substances: Magnesium Sodium Chloride Oxygen Magnesium Chloride en_US
dc.title Effects of age and magnesium ions on oxygen toxicity in the neonate chicken en_US

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  • Undersea Biomedical Research Journal
    The Undersea Baromedical Research journal was published by the Undersea Medical Society, Inc. (now the Undersea and Hyperbaric Medical Society) quarterly from 1974 to 1992 when the name changed to the Undersea and Hyperbaric Medicine Journal.

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