Absence of antiarrhythmic effects of helium in patients with spontaneous premature ventricular beats at rest

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Absence of antiarrhythmic effects of helium in patients with spontaneous premature ventricular beats at rest

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Title: Absence of antiarrhythmic effects of helium in patients with spontaneous premature ventricular beats at rest
Author: Wade, CE; Banister, EW; Baker, DG; Lin, YC
Abstract: Six patients with spontaneously occurring arrhythmias were studied to assess the antiarrhythmic properties of helium. The patients were divided into two subgroups breathing air, helium-oxygen (heliox), and nitrogen-oxygen (nitrox) in an alternating sequence during successive 20-min periods under continuous ECG surveillance at rest. There were no significant reductions in spontaneously occurring premature ventricular beats while breathing heliox, compared to breathing air of nitrox. Alternating the breathing gases in this manner caused no change in plasma concentration of electrolytes or in activity of serum glutamic-oxaloacetic transaminase or lactic acid dehydrogenase. We conclude that helium does not affect spontaneously occurring chronic premature ventricular beats in conscious resting man when it is breathed for a period of up to 20 min. Adult Air Arrhythmia/blood/*drug therapy Aspartate Aminotransferases/blood Electrolytes/blood Female Helium/*therapeutic use Human L-Lactate Dehydrogenase/blood Male Middle Aged Nitrogen/therapeutic use Oxygen/therapeutic use Support, U.S. Gov't, Non-P.H.S. Support, U.S. Gov't, P.H.S.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: PMID: 538859
http://archive.rubicon-foundation.org/2865
Date: 1979

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  • Undersea Biomedical Research Journal
    The Undersea Baromedical Research journal was published by the Undersea Medical Society, Inc. (now the Undersea and Hyperbaric Medical Society) quarterly from 1974 to 1992 when the name changed to the Undersea and Hyperbaric Medicine Journal.

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