Water immersion and the kidney: implications for volume regulation

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Water immersion and the kidney: implications for volume regulation

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dc.contributor.author Epstein, M en_US
dc.date.accessioned 2006-08-24T22:35:06Z
dc.date.available 2006-08-24T22:35:06Z
dc.date.issued 1984 en_US
dc.identifier.other Undersea Biomed Res en_US
dc.identifier.uri PMID: 6567431 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/2983
dc.description Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.description.abstract Studies from this laboratory have demonstrated that head-out immersion in isothermic water causes a cephalad redistribution of blood volume. The resultant central hypervolemia induces a marked natriuresis and diuresis and suppression of plasma renin activity, plasma aldosterone, and plasma arginine vasopressin. All of these changes are thought to be attributable to stimulation of cardiopulmonary receptors. Immersion also produces an augmentation of prostaglandin E (PGE) excretion, which reflects increased renal PGE synthesis. The ability of immersion in induce a prompt and profound central hypervolemia, without concomitant alterations in plasma composition, indicates that immersion might be a preferred investigative tool for assessing the effects of volume expansion on renal function and hormonal responsiveness in both normal individuals and patients with edematous disorders. In addition, this model constitutes an appropriate tool for simulating weightlessness. Blood Volume Catecholamines/blood Comparative Study Diuresis Human Immersion/*physiopathology Kallikreins/physiology Kidney/metabolism/*physiopathology Kinins/physiology Natriuresis Natriuretic Agents Proteins/metabolism Renin-Angiotensin System Sodium/metabolism Vasopressins/urine en_US
dc.format.extent 1430235 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.source.uri null en_US
dc.subject human en_US
dc.subject Immersion Diuresis en_US
dc.subject volume regulation en_US
dc.subject Undersea Biomed Res. 1984 Jun;11(2):113-21. en_US
dc.subject.mesh Blood Volume Catecholamines/blood Comparative Study Diuresis Human Immersion/*physiopathology Kallikreins/physiology Kidney/metabolism/*physiopathology Kinins/physiology Natriuresis Natriuretic Agents Proteins/metabolism Renin-Angiotensin System Sodium/metabolism Vasopressins/urine en_US
dc.title Water immersion and the kidney: implications for volume regulation en_US

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  • Undersea Biomedical Research Journal
    The Undersea Baromedical Research journal was published by the Undersea Medical Society, Inc. (now the Undersea and Hyperbaric Medical Society) quarterly from 1974 to 1992 when the name changed to the Undersea and Hyperbaric Medicine Journal.

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