Desmopression Prevents Immersion Diuresis and Improves Physical Performance After Long Duration Dives

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Desmopression Prevents Immersion Diuresis and Improves Physical Performance After Long Duration Dives

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dc.contributor.author Nyquist, PA en_US
dc.contributor.author Schrot, J en_US
dc.contributor.author Thomas, JR en_US
dc.contributor.author Hyde, DE en_US
dc.contributor.author Taylor, WR en_US
dc.date.accessioned 2006-09-05T21:36:49Z
dc.date.available 2006-09-05T21:36:49Z
dc.date.issued 2005 en_US
dc.identifier.govdoc ADA448907 en_US
dc.identifier.govdoc NMRC-2005-001 en_US
dc.identifier.govdoc BUMED-DN241126 en_US
dc.identifier.govdoc XB-BUMED en_US
dc.identifier.other BLOOD FLOW en_US
dc.identifier.other SERUM OSMOLALITY en_US
dc.identifier.other URINE OUTPUT en_US
dc.identifier.other *DESMOPRESSIN en_US
dc.identifier.other *PHYSICAL PERFORMANCE en_US
dc.identifier.other PE6371N en_US
dc.identifier.other WUNMRCM00990131428 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/3592
dc.description Citation Status: Active; Citation Classification: Unclassified; Title Classification: Unclassified; Report Classification: Unclassified; Identifier Classification: Unclassified; Abstract Classification: Unclassified; Distribution Limitation(s): 01 - APPROVED FOR PUBLIC RELEASE; Information provided by the Department of Defense and the Defense Technical Information Center (http://www.dtic.mil/) is considered public information and may be distributed or copied unless otherwise specified. Use of appropriate byline/photo/image credits is requested. en_US
dc.description.abstract Water immersion causes dehydration affecting blood flow to muscle, skin and reduces blood volume. Desmopressin inhibits urine production preventing immersion-induced blood volume loss. This study had two goats 1) examine the effect of Desmopressin on immersion diuresis and 2) any subsequent effects on physical and cognitive performance. Twenty U.S. Navy divers participated in a pool study (72 deg F) and field study (80-82 deg F) for 3.5 hat 10-15 feet of seawater; each completed a control and experimental dive. Hydration and performance were measured. Before the experimental dive, subjects received 40 microg of Desmopressin intranasally. Before and after each dive blood samples were taken, performance assessments were performed, and urine, electrolyte and hematologic values were determined. Desmopressin reduced immersion diuresis while maintaining post dive physical performance. Desmopressin significantly attenuated immersion diuresis and maintained aerobic capacity during 3.5 h dives in warm water. en_US
dc.format.extent 736363 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights Citation Status: Active; Citation Classification: Unclassified; Title Classification: Unclassified; Report Classification: Unclassified; Identifier Classification: Unclassified; Abstract Classification: Unclassified; Distribution Limitation(s): 01 - APPROVED FOR PUBLIC RELEASE; Information provided by the Department of Defense and the Defense Technical Information Center (http://www.dtic.mil/) is considered public information and may be distributed or copied unless otherwise specified. Use of appropriate byline/photo/image credits is requested. en_US
dc.subject DIVING en_US
dc.subject DEHYDRATION en_US
dc.subject HYDRATION en_US
dc.subject DIURESIS en_US
dc.subject NAVAL PERSONNEL en_US
dc.subject PERFORMANCE(HUMAN) en_US
dc.subject COGNITION en_US
dc.subject MUSCLES en_US
dc.subject BLOOD VOLUME en_US
dc.subject HEMATOLOGY en_US
dc.subject URINE en_US
dc.subject BLOOD CIRCULATION en_US
dc.subject ELECTROLYTES en_US
dc.subject SEA WATER en_US
dc.subject DIVERS en_US
dc.subject IMMERSION en_US
dc.title Desmopression Prevents Immersion Diuresis and Improves Physical Performance After Long Duration Dives en_US

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