Effect of 2.1 MPa and 4.1 MPa H2O2 exposure on auditory brain stem evoked potential in mice.

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Effect of 2.1 MPa and 4.1 MPa H2O2 exposure on auditory brain stem evoked potential in mice.

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dc.contributor.author Weibing, X
dc.contributor.author Jun, L
dc.contributor.author Zheng, M
dc.contributor.author Fengtao, Y
dc.contributor.author Hexiang, Z
dc.date.accessioned 2007-01-26T03:08:27Z
dc.date.available 2007-01-26T03:08:27Z
dc.date.issued 2005
dc.identifier.citation Undersea Hyperb Med. 2005 Sep-Oct;32(5):391-6. en
dc.identifier.other PMID- 16457087
dc.identifier.uri http://archive.rubicon-foundation.org/4055
dc.description Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. en
dc.description.abstract Brain auditory evoked potential (BAEP) in mice exposed to hyperbaric H2O2 pressure was monitored to reveal the correlation between altered synaptic transmission and hydrogen narcosis or isobaric HPNS. Inter peak latencies and wave amplitudes were selected as indices of assessment. The animals were exposed either to He-O2 or H2-O2 at 2.1 MPa and 4.1 MPa. Results showed that synaptic transmission was inhibited to various extents. The inhibition was partly due to the narcotic effect of hydrogen, which was added to the effect caused by hydrostatic pressure. On the other hand, asymmetrical reaction of each segment in the neuro-network might be responsible for the occurrence of HPNS. en
dc.format.extent 730098 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US en
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en
dc.subject Decompression/methods en
dc.subject Animal en
dc.subject Evoked Potentials, Auditory, Brain Stem/*drug effects/physiology en
dc.subject Helium/administration & dosage/pharmacology en
dc.subject mice en
dc.subject High Pressure Neurological Syndrome/physiopathology en
dc.subject Hydrogen/administration & dosage/*pharmacology en
dc.subject Hydrostatic Pressure en
dc.subject Inert Gas Narcosis/physiopathology en
dc.subject Oxygen/administration & dosage/*pharmacology en
dc.subject Synaptic Transmission/*drug effects/physiology en
dc.title Effect of 2.1 MPa and 4.1 MPa H2O2 exposure on auditory brain stem evoked potential in mice. en
dc.type Article en

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