[abstract] DCI SYMPTOMS DO NOT APPEAR TO FORM SYNDROMES

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[abstract] DCI SYMPTOMS DO NOT APPEAR TO FORM SYNDROMES

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Title: [abstract] DCI SYMPTOMS DO NOT APPEAR TO FORM SYNDROMES
Author: Dear, GdeL; Vann, RD; Pieper, CF; Bute, BP; Uguccioni, DM; Thalmann, ED
Abstract: BACKGROUND: A syndrome is a collection of signs and symptoms which occur together to define a condition or disease. We wanted to see if the symptoms of DCI (AGE and DCS) as reported from the field would form identifiable syndromes which might be useful for categorization or in choosing treatment protocols. Data collected on 2,822 DCI cases by the Divers Alert Network (DAN) between 1989 and 1994 were analyzed. Each case had a Diving Accident Reporting Form (DARF) which listed up to 6 symptoms and some dive characteristics such as rapid ascent and/or whether the diver had run out of air (analyzed as variable RAPOUT) and time of symptom onset (TSO). The reporting physicians classified the individual as DCSI, DCSII, or AGE according to their clinical judgment and training. These categories were not specifically defined on the DARF. METHODS: The statistical procedure of Principle Component Analysis (PCA) was used. PCA constructs symptoms groups (Components) in such a way as to maximize the variance explained by each Component. Once constructed, each Component can be used to compute a quantitative score for each individual case whose value depends on the types of symptoms present. The means and variances of these individual scores can be compared for different populations (e.g. DCS vs. AGE) to assess for differences. RESULTS: When a subset of 20 symptoms, TSO less than 10 min and RAPOUT were analyzed, the first Component explained only 10.5percent of the total variance and the first 3 Components only 24percent. A syndrome would be present if 3 or 4 symptoms accounted for most of any Component's score. This was not found. However, when all 20 symptoms, TSO less than 10 and RAPOUT were taken into account, the lower 25th percentile of the first Component score distribution for cases classified as AGE was greater than the upper 75th percentile for those classified as DCSI or DCSII, providing some degree of discrimination between the groups. CONCLUSION: The presenting symptoms as listed on the DARF do not form clearly identifiable syndromes. However, at least one Principle Component showed some success in discriminating cases classified as AGE from other forms of DCI. (Supported by Divers Alert Network).
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/407
Date: 1997

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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