[abstract] MECHANISM OF C.N.S. SYMPTOMS: THE LUNG AS A BUBBLE TRAP.

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[abstract] MECHANISM OF C.N.S. SYMPTOMS: THE LUNG AS A BUBBLE TRAP.

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Title: [abstract] MECHANISM OF C.N.S. SYMPTOMS: THE LUNG AS A BUBBLE TRAP.
Author: Hills, BA; Butler, BD
Abstract: Several neurologic forms of decompression sickness are generally attributed to arterial emboli. It is therefore highly desirable to know how effective the lung is in trapping the many microbubbles which can be detected in the venous system during decompression - most of which are asymptomatic. In this study, microbubbles of 40-300 um dia. calibrated to +/- 2 um by a Coulter counter are injected directly into the right atrium or pulmonary artery of anesthetized dogs. Bubbles which fail to be trapped by the lung are detected transcutaneously by a new 8 MHz Doppler probe placed over the left femoral artery with both audial and graphical signal evaluations. Several pathologic conditions which might impair the efficiency of the lung as a bubble filter have been induced in the dogs, including: 1. hypovolemia (30-40 percent of total blood loss), 2. chronic oxygen poisoning (20 hours at 1.5 Atm O2), 3. overload with microbubbles (pulmonary vascular congestion), 4. elevated carbon dioxide, 5. recompression. Preliminary findings indicate that these can facilitate the escape of venous bubbles into the arterial system to varying degrees. This indicates a warning against the excessive use of oxygen during decompression or over-recompression of a limb bend in case either action may precipitate neurologic symptoms. This study is also concerned with the use of pulmonary vascular asoconstrictors as a pharmacological approach to the prevention of neurologic decompression sickness.
URI: http://archive.rubicon-foundation.org/4344
Date: 1978

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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