[abstract] PLASMA LIPID ALTERATIONS FOLLOWING DECOMPRESSION IN HUMANS AND ANIMALS.

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[abstract] PLASMA LIPID ALTERATIONS FOLLOWING DECOMPRESSION IN HUMANS AND ANIMALS.

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Title: [abstract] PLASMA LIPID ALTERATIONS FOLLOWING DECOMPRESSION IN HUMANS AND ANIMALS.
Author: Cockett, ATK; Cockett, WS; Pauley, SM; Pilmanis, AA
Abstract: Lipid emboli interacting with nitrogen bubbles are now felt to be of primary concern in the genesis of decompression sickness. Human volunteers were asked to dive to depths of 100 to 200 feet using SCUBA and breathing air. Bottom time for each separate dive never exceeded standard decompression tables allowing continuous ascent to surface. Fasting pre-dive blood samples for lipid studies were obtained from volunteers at least 3 hours after a non-fat meal. Post-dive samples were obtained within 15 minutes after surfacing from the dive. Thirteen splenectomized dogs under anesthesia were overcompressed in a chamber to 165 feet for 1hour. Decompression was carried out at the rate of 15 feet per minute. Fasting pre-dive and 3 hour post-dive plasma samples were analyzed for cholesterol, phospholipids, triglycerides and total lipids. Our results in 13 dogs revealed significant post-dive elevations in plasma cholesterol (144mg% to 160mg%), phospholipids (298mg% to 325mg%), triglycerides (26.7mg% to 37mg%), and total lipids (518mg% to 561mg%). The 30 volunteers demonstrated significant elevations in cholesterol (192mg% to 203mg%), unesterified fatty acids (.515m~q/L to .686m~q/L), and phospholipids (267mg% to 304mg%) following their dives. Decompression sickness or bends was not encountered. Hemo-concentration was seen in nearly all divers. We believe that antilipemic agents are very important in treating decompression sickness. Our findings indicate that volunteer divers who are asymptomatic manifest trends which suggest lipid alterations. These alterations can lead to silent lipid embolization.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 10-11, 1974. Hilton Hotel, Washington, D.C. (http:www.uhms.org)
URI: http://archive.rubicon-foundation.org/48
Date: 1974

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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