Human Central Nervous System Oxygen Toxicity Data from 1945 to 1986.

Abstract

This report contains a summary of all known results from controlled human exposures to hyperbaric O2. The data were collected for analysis and development of predictive models relating the risk of developing a symptom of central nervous system O2 toxicity as a function of time, depth, and condition of exposure. Data were obtained from publications, technical reports and verified by original records and log books. A total of 2,170 exposures, at depths ranging from 12 feet of sea water (fsw) to 100 fsw for up to 240 min are included. The data consist of exposure time, depth, fraction of inspired 0 2, temperature, whether or not subjects exercised, whether they were immersed in water or exposed in a dry chamber, and outcome of the exposure, i.e., whether a symptom developed or the exposure was completed safely. Studies conducted under the following conditions were found: dry, no exercise; dry, exercise; immersed, no exercise; immersed, exercise; the final category was divided into old (before 1972) and new.