[abstract] THE EFFECTS OF HYPERBARIC OXYGEN THERAPY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS

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[abstract] THE EFFECTS OF HYPERBARIC OXYGEN THERAPY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS

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Title: [abstract] THE EFFECTS OF HYPERBARIC OXYGEN THERAPY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS
Author: Kinaci, N; Kinaci, S; Alan, M; Elbuken, E
Abstract: BACKGROUND: There are many theories as to the cause of Autism Spectrum Disorders (ASD) such as abnormal cerebral blood flow to areas of the brain. Genetics, heavy metal burden, infectious agents are predisposing factors for ASD. Many cases of ASD today are, in fact, cases of gut-brain inflammation secondary to toxic heavy metal poisoning. MATERIALS AND METHODS: We performed a retrospective review in search of 108 children with ASD (85 males, 23 females) between the ages 3-12, who had done basal and control brain perfusion Single-Photon Emission Computed Tomography (SPECT) Scans between the years 2004-2009. We reviewed Dimercaptosuccinic acid (DMSA) provocated urine toxic metals profiles, Magnetic Resonance Imaging (MRI) results, SPECT scans, special questionnaires of 108 children and Autism Treatment Evaluation Checklist (ATEC) done by parents (54 of) and clinicians / therapists (other 54 of) of these children. They were all applied 50 sessions Hyperbaric Oxygen Therapy (HBOT) for each patient at 1.5 ATA for 60 minutes/daily. RESULTS: All 108 cases had elevated or very elevated levels of lead, 61 of them had mercury and most of them were in conjunction with some other toxic heavy metals. Before HBOT all of the patients revealed focal areas of decreased perfusion in temporal lobe of the brain. We also detected decreased perfusion in 79 males and in 16 females at frontal lobes and in 54 males and in 12 females at other areas of the brain. By contrast all patients had normal MRI findings. We determined that, after HBOT perfusion was improved 82.40% (89 of 108) in the temporal, 85.26% (81 of 95) in the frontal and 75.75% (50 of 66) in other areas. On ATEC of 54 patients done by clinicians/therapists, we determined that, 79% improvement were at Speech/Language/Communication, 85,5% improvement were at Sociability, 87% improvement were at Sensory/Cognitive Awareness and 75,2% improvement were at Health/Physical/Behavior. CONCLUSIONS: HBOT which now being used for children with ASD is to address the neuroinflammatory component of this disorder. This study showed behavioral, physical and brain perfusion improvements after HBOT and positive or negative effects of HBOT in children with ASD, who have brain inflammation secondary to high levels of toxic heavy metals.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting, Las Vegas, Nevada, USA. (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/9163
Date: 2009

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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