The pathway to drive decompression microbubbles from the tissues to the blood and the lymphatic system as a part of this transfer.

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The pathway to drive decompression microbubbles from the tissues to the blood and the lymphatic system as a part of this transfer.

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dc.contributor.author Hugon, J en_US
dc.contributor.author Barthelemy, L en_US
dc.contributor.author Rostain, JC en_US
dc.contributor.author Gardette, B en_US
dc.date.accessioned 2011-10-15T04:30:04Z
dc.date.available 2011-10-15T04:30:04Z
dc.date.issued 2009 en_US
dc.identifier.citation Undersea Hyperb Med. 2009 Jul-Aug;36(4):223-36. en_US
dc.identifier.isbn 1066-2936 en_US
dc.identifier.other 20088241 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/9324
dc.description Undersea and Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc. en_US
dc.description.abstract The formation sites of the microbubbles that are routinely detected in the bloodstream at precordial level by Doppler after a decompression are reviewed and discussed here. First, microbubbles could form on the endothelium lumen wall of the capillaries, at specific nanometric sites, but the release mechanism of such small emerging entities remains puzzling. They could be also formed from pre-existing gas nuclei present in the blood when favorable local hydrodynamic/supersaturation conditions generate microcavitation and tribonucleation phenomena. Finally, tissues could represent large pools for microbubble formation and amplification. Nevertheless, it remains to explain what the potential pathways are to drive them to the blood. Knowing that the permeability of most of the blood capillary network is quite low, an alternative is proposed for such transport. The lymphatic system, which drains the interstitial fluid to guarantee the fluid balance of tissues, could allow the transfer of micrometric elements like stabilized microbubbles formed in tissues on long distances. A final rejection in the bloodstream at the termination of both right lymphatic and thoracic ducts can be expected. The characteristics of this slow transport, activated by the muscular pump, could explain the detection on long periods of massive venous gas emboli. en_US
dc.language.iso en en_US
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en_US
dc.subject bubbles en_US
dc.subject doppler en_US
dc.subject methods en_US
dc.subject.mesh Animals en_US
dc.subject.mesh Biological Transport/physiology en_US
dc.subject.mesh Capillary Permeability en_US
dc.subject.mesh Decompression en_US
dc.subject.mesh Decompression Sickness/*blood/etiology/ultrasonography en_US
dc.subject.mesh Endothelium, Vascular en_US
dc.subject.mesh Heart Valves/physiology en_US
dc.subject.mesh Humans en_US
dc.subject.mesh Lymph/physiology en_US
dc.subject.mesh *Lymphatic Vessels/anatomy and histology/physiology en_US
dc.subject.mesh *Microbubbles en_US
dc.subject.mesh Veins en_US
dc.title The pathway to drive decompression microbubbles from the tissues to the blood and the lymphatic system as a part of this transfer. en_US
dc.type Article en_US

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