Transfer of Selected Pulmonary O2 Poisoning Data Components of The Oxygen Research Program to US Navy Experimental Diving Unit

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Transfer of Selected Pulmonary O2 Poisoning Data Components of The Oxygen Research Program to US Navy Experimental Diving Unit

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Title: Transfer of Selected Pulmonary O2 Poisoning Data Components of The Oxygen Research Program to US Navy Experimental Diving Unit
Author: Lambertsen, CJ; Clark, JM; Gelfand, R; Hopkin, E
Abstract: Predictive studies V: Defining human organ tolerance to continuous oxygen exposure. The collaborative Predictive Studies V Program was performed to determine the rates of development and recovery in oxygen poisoning produced by uninterrupted oxygen breathing over essentially the full range of oxygen exposure useful in diving and hyperbaric therapy. Extending from prior individual projects, the multiyear, multidisciplinary Program investigated measurable physiologic and toxic effects of oxygen upon selected organ and tissue functions at 0.2, 1.5, 2.0, 2.5, and 3.0 ATA of inspired oxygen. This Program represented the first systematic investigation of human pulmonary oxygen poisoning at oxygen pressures greater than 2.0 AT A. It also represents the only definitive and correlative investigations at pressures greater than 1.0 AT A of oxygen poisoning effects in other human organ systems and tissues, including brain, heart, liver, kidney, skeletal muscle, and endocrine organs.
Description: The items forming the Rubicon Research Repository Christian J. Lambertsen collection are generously donated by the Lambertsen Family. All items in this collection are released through Creative Commons Attribution + Noncommercial + ShareAlike (BY-NC-SA) licenses in an attempt to encourage the use of these works to further scientific understanding of physiology.
URI: http://archive.rubicon-foundation.org/10785
Date: 2003

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